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The transgene construct contains the rat nestin second intron enhancer fused to an hsp68 (Hspa1b) minimal promoter driving a 1.6 kb cre sequence fused to the tamoxifen-inducible mutant estrogen receptor (Esr1*). The linearized construct was microinjected into pronuclei of fertilized C57BL/6 eggs. Three lines of nestin-cre/Esr1* mice were generated. (J:156372)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
