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The construct had 3.5 kb of sequence flanking exon 2 and the entire intron 2 sequence of the Csf1r gene driving expression of EGFP. This construct was injected into pronuclei of (C57BL/6 x CBA)F1 fertilized eggs. 5 lines that transmitted the transgene were generated, and EGFP expression was readily detected in peritoneal, bone marrow-derived, and broncho-alveolar lavage macrophages from all lines. (J:156311)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
