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A 42 bp insertion encoding a 14 amino acid BAP tag was inserted into the fourth exon 17 amino acids upstream of the C terminus. In addition a floxed neo resistance cassette was inserted and then removed by Cre mediated recombination leaving a loxP site in the third intron. Repressor activity of the resulting tagged protein is impaired making this a hypomorphic allele. Protein expression is increased compared to wild-type controls. (J:155378)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
