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The construct contains the human glial fibrillary acidic protein (GFAP), a tripartite intron composed of an adenovirus splice donor and immunoglobulin G splice acceptor site, the open reading frame of cre/ERT2 (cre fused to an improved mutant human estrogen receptor), and a human growth hormone polyA site. The linearized 5.3kb fragment was injected into FVB/N fertilized oocytes. Two lines were found to express cre protein and one line designated 1 (called GCTF in J:156009) was analyzed further. (J:156009)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
