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This mutant allele retains the 5' region of the gene through the first 20 base pairs of exon 2, which encode the first zinc finger of the protein. A lacZ-PGK-neo cassette has replaced the remaining 3' portion of exon2 and all of intron 2 and exon3, including the second and third zinc finger coding sequences. Neither RT-qPCR analysis nor in situ hybridization to E10.5 embryos detected any transcripts. (J:155855)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
