LoxP sites flanking exons 2 and 3 as well as an FRT flanked neomycin expression cassette were inserted by homologous recombination. The neomycin resistance cassette was then removed by flp mediated recombination. (J:155298)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count