This transgene results from the coinjection of two constructs derived from a C57BL/6 hybridoma cell line responsive to BALB/c splenocytes. The Tcra construct under the control of the human CD2 promoter contains a cDNA including V alpha 8.5 sequence and the Tcrb construct under the control of the mouse Cd4 promoter (without the intronic silencer) contains a cDNA including V beta 13 sequence. (J:155848)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F2
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Insertion
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16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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