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Nuclear localizing Cre recombinase is expressed under control of a 5.4-kb genomic DNA fragment containing the Hes7 (hairy and enhancer of split 7 (Drosophila)) promoter. Cre mRNA is expressed in the presomitic mesoderm (PSM) of the E10.5 embryo, and its expression appears to oscillate. In doubly transgenic embryos bearing this transgene and a lacZ reporter transgene, X-gal staining is observed throughout the PSM and in the somites and their derivatives at E7.5-E10.5. (J:124102)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
