A loxP site was inserted 300 bp upstream of exon 2 and a floxed hygromycin (Hph) antibiotic-resistance marker was inserted 50 bp downstream of exon 4. Cre mediated recombination removed the Hph cassette leaving exons 2 through 4 floxed. (J:155421)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count