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The human promoter drives expression of cre followed by an IRES sequence and EGFP in granulocytes and a fraction of myelomonocytic progenitors. Two founders were generated (no line information given). a A single copy of the transgene integrated at a single site on chromosome 5 (137,042,580-137,086,690; mouse mm10). This insertion leads to a 44 kb deletion of the host genome, resulting in complete deletion of the Serpine1 gene and partial deletion of the Ap1s1 gene. (J:94778, J:323640)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
