A construct containing a floxed neo cassette with 3 polyadenylation sites, Gli2 cDNA lacking the first 280 N-terminal amino acids, an IRES sequence, and EGFP cDNA was inserted into the locus. Cre mediated recombination is required to obtain expression of the Gli2 cDNA and EGFP. (J:154905)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count