A CAG promoter drives expression of an EGFP/tetanus toxin light chain (tetX) fusion preceded by a floxed STOP signal and an frt flanked mCherry and STOP signal. Cre mediated removal of the first STOP signal is required for expression of mCherry. Cre and Frt mediated recombination are required to remove both STOP signals to allow for expression of the EGFP/tetX fusion. (J:154944)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
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--
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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