An frt flanked neo and kan cassette with a 3' loxP site was inserted upstream of exon 2, and an additional loxP site was inserted downstream of exon 8. Germ line, flp mediated recombination removed the selection cassette leaving exons 2 through 8 floxed. (J:154779)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count