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The transgene was constructed from a modification of BAC RP24-149-K18 such that a cassette containing an improved cre gene fused to the modified human ESR1 receptor (ERT2) and an IRES-EGFP followed by an frt-flanked neo cassette was inserted at the start of the Slc16a8 open reading frame. Transient flp expression in removed the neo cassette in bacterial cells. Cre activity is detected in the retinal pigment epithelium. (J:154671)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
