The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1011bp between positions 55619824-55620834 of Chromosome 13 (Build GRCm39). The entire coding region was replaced by a cassette containing the lacZ gene expressed under control of the endogenous promoter and an independently expressed neomycin resistance gene. Immunoblotting of brain lysates confirmed the absence of protein expression in homozygous mutant mice. (J:136110, J:237776)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
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1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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