A loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 5. Germ line, cre mediated recombination removed the neo cassette leaving exons 3 through 5 floxed. (J:154784)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count