Germ line, flp mediated recombination removes the LacZ gene and neo cassette leaving exon 2 floxed. A 35% reduction in protein expression was confirmed by western blot analysis on extracts from homozygotes. (J:154794)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count