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The open reading frame was replaced with EGFP and a floxed neo cassette. Germ line, cre mediated recombination removes the neo cassette. The reduction in transcript expression was confirmed by quantitative PCR on immune cell population extracts from heterozygous mice. (J:151077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
