By homologous recombination in ES cells a single loxP site was inserted into intron 3 and FRT flanked PGK-neo cassette followed by loxP was inserted into intoron 4, resulting in Exon 4 flanked by loxP sites. (J:82809, J:254435)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count