The targeting construct contains a CMV promoter followed by a LoxP66 site, a cDNA encoding an antisense mouse Bmi1, an IRES, an eGFP cassette and a LoxP71 followed by a PGK promoter neo cassette. Cre expression enables the inversion of the antisense Bmi1. (J:187257)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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