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The 9.2 Kb regulatory fragment 1 is followed by an SV40 splice donor and acceptor, an IRES sequence, and a cre recombinase gene. Several founders were generated and several lines were created (including lines B, D, and L1). Line L1 exhibits cre activity at E13.5 in lung endothelial cells and at E15.5 in the lung endothelial cells and extraembryonic vessels. (J:130020)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
