This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. Three lines were created (lines 1, 4, and 5-1) with differing levels of activity (high, medium, and low, respectively) and leakiness (high, low and none, respectively). (J:110145)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count