A conditional gene trap vector flanked by loxP, lox511 and FRT sites inserted between exons 20 and 21. The gene trap construct is designed such that in the absence of recombinase the gene trap resided in the mutagenic orientation (Ubr5mt); (2) after flp-mediated recombination, in the non-mutagenic orientation (Ubr5WT*); and (3) after cre-mediated recombination, in the permanent mutagenic orientation (Ubr5mt*). (J:236026)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
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1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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