A conditional-ready gene trap cassette with FRT, F3, loxP, and Lox5171 sites upstream of a beta-geo reporter followed downstream by loxP, lox5171, FRT, and F3 sites in inverse orientation, was inserted into exon 1. This insertion is in the original gene-trapped configuration so that transcription is stopped at the beta-geo reporter, yielding a null allele, which can be excised into a functional allele through Flp- or Cre-mediated excision. (J:236978)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
6
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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