Exon 11 was replaced with one in which nucleotide substitutions resulting in the amino acid substitution of tyrosine for asparagine at position 641 (N641Y). A self-excising neo cassette was inserted upstream of exon 11 and removes itself leaving a single loxP site. (J:154118)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count