Log In|Sign Up
EN
This transgene contains 706 base pairs of 5' flanking sequence containing the promoter of the rat pro-opiomelanocortin gene followed by the coding sequence for Cre recombinase with an amino-terminal nuclear localization signal (nlsCre), a synthetic intron, and SV40 splice and polyadenylation signals. Progeny of mice bearing this transgene crossed to lacZ Cre reporter mice exhibited large numbers of X-gal staining cells in the intermediate lobe and lesser staining in the anterior lobe of the pituitary gland. (J:80158)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
