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A targeting vector was designed to encode a sequence for the neomycin resistance gene with a polyadenylation signal (STOP sequence), flanked by rox sites (dre recombinase recognition sequences) and followed by the lacZ gene. This was targeted to the Gt(ROSA)26Sor locus in R1 ES cells. Following dre recombinase-mediated excision, beta-galactosidase expression can be detected in cells which underwent recombination. (J:154134)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
