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A plasmid in which the CAG (CAGGS) promoter drives the bacteriophage D6 site-specific recombinase (dre). This is followed by an IRES-puromycin sequence for selection. The linearized construct was electroporated into R1 ES cells, and single-copy clones were injected into 8-cell embryos. Germline transmission was obtained for one of these clones. (J:154134)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
