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A neomycin resistance cassette in which the coding sequence and polyadenylation site are flanked by loxP sites (PGK-loxP-neo-pA-loxP) was inserted 4.34 kb 3' of (centromeric to) the third, last coding exon of Ascl2, between Chr 7 imprinting center 1 (IC1/H19 DMR) and IC2/KvDMR1. Cre recombinase deletion of the floxed segment left the PGK promoter and a loxP site. (J:153719)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
