A loxP site was inserted upstream of exon 4 and a floxed neo allele was inserted downstream of exon 5. Transient cre expression mediated removal the neo cassette leaving exons 4 and 5 floxed. (J:153474)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count