Germ line, cre recombination removes the upstream floxed STOP cassette inserted into the locus allowing CAG-driven expression of SCAT3.1 (an apoptosis-sensitive reporter composed of a fusion of ECFP and the Venus EYFP analog connected by a caspase 3 cleavable peptide). (J:153768)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count