The CAG-driven SCAT3.1 (caspase-3-sensitive fusion protein) with an upstream floxed STOP cassette was inserted into the locus. SCAT3.1 contains a fusion of ECFP and the Venus EYFP analog connected by a caspase 3 cleavable peptide. Removal of the floxed STOP cassette is required for the expression of the caspase-3-sensitive reporter fusion. (J:153768)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count