Most of exon 2 was replaced with a targeting vector including 1.2 kb of the Nanog promoter as a 5' arm, the firefly luciferase gene, SV40 polyadenylation signal sequence, loxP-flanked PGK-neo cassette, and 1.4 kb of intron 2 as a 3' arm. (J:153798)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count