Log In|Sign Up
EN
Exon 1 was replaced with a lacZ with a nuclear localization signal and a floxed cre-neo cassette, which excises itself. Exon 2 was also modified to introduce STOP codons in all three frames. The absence of protein expression as confirmed by immunohistochemistry on E12.5 spinal cord sections. (J:153212)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
