A loxP site was inserted upstream of exon 10 and a floxed neo cassette was inserted downstream of exon 12 via homologous recombination. The neo cassette was then removed by Cre mediated recombination leaving exons 10 - 12 floxed. (J:115188)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count