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The env gene from the LAV strtain of HIV-1 was truncated to encode gp120 amino acids 1-509 and inserted in exon 1 of a modified murine Gfap gene. Five lines (2, 3,10, 16, 37) were established which varied in level of expression. Level of expression did not correlate with transgene copy number. This is a high expressor line. (J:146427)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
