The putative transcription regulatory element of the mouse Aire gene was used to drive expression of cre recombinase. The linearized construct was injected into fertilized C57BL/6 oocytes. Two transgenic founders were generated and one was selected for further study. (J:152798)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count