A targeting vector was designed to insert loxP sites to flank the first three exons, including the start codon, the N-terminal repression domain, nuclear localization signal and part of the T-box domain. In addition, an frt flanked neomycin resistance cassette was inserted into the intron after the third exon. (J:153100)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count