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Bigenic mice contain a rtTA driven by the mouse Col2a1 promoter and human COMP, with the deletion del469D found in patients with pseudoachondroplasia, driven by the tetO promoter. Three lines were generated (no line names given). (J:152756)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
