Exon 23 was flanked by loxP sites. The neomycin selection cassette was excised in vitro. Mutant ES cells retaining the neo cassette will not be used to create mice. (J:181090)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count