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A 3kb genomic fragment containing a truncated Pcp2 enhancer and gene drives cre/ERT2 followed by an IRES-ALPP (human placental alkaline phosphatase) sequence. The construct was injected into FVB/N oocytes and four founders were obtained. The line displaying the strongest expression in embryonic Purkinje cell (PC) clusters and adult medial-lateral PC stripes was chosen for further analysis. (J:152951)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
