A loxP site was inserted into intron 6 and a second loxP site and an frt flanked neo cassette were inserted into intron 8 via homologous recombination. Frt mediated recombination removed the neo cassette leaving exons 7 and 8 floxed. (J:152712)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count