Log In|Sign Up
EN
This transgene comprises two tandem copies of a 0.7-kb DNA fragment containing the node-specific enhancer (NDE) of the Nodal gene, 1.2 kb of 5' flanking DNA from the Nodal locus containing the promoter, and the Cre recombinase coding sequence. Beta-galactosidase expression in progeny of mice with this transgene and animals bearing a lacZ Cre reporter transgene is first detected by X-Gal staining in the region of the posterior node of 2-somite-stage embryos; this activity becomes stronger as the embryos develop. (J:82703, J:104881)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
