The BAC RP23-278N11 was used to make a transgene expressing Gpbar1. It was modified to contain the rabbit beta-globin intron, an inactive cre/ERT2 fusion, and frt-flanked neo cassette downstream of the Vil1 promoter for genotyping purposes. The neo cassette was removed by germ line, flp mediated recombination. One line was created with 6 copies of the transgene and Gpbar1 expression restricted to most tissues normally expression Gpbar1. (J:152388)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count