A floxed beta-Geo cassette was inserted in intron 16 and an additional loxP site was inserted in intron 13. Exons 14-16 are thus flanked by loxP sites. Mice were crossed with transgenic mice carrying an unspecified Zp3-cre transgene to excise exons 14-16 and the beta Geo cassette. (J:152382)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count