A loxP site was inserted upstream of Mir143 and an frt-flanked neo cassette with a downstream loxP site was inserted downstream of Mir145. Flp-mediated recombination followed by cre-mediated recombination or cre-mediated recombination alone removed the selection cassette, Mir143, and Mir145. (J:152458)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S/SvEv
Targeted
Insertion, Intergenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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