The transgenic construct consists of a bacterial artificial chromosome (BAC) clone 467.8 encoding a 190 kb segment from human 22q11.2 including TXNRD2, COMT, and ARVCF. Transgenic mice were generated by microinjection into FVB mouse embryos. Mice have one to two copies of the transgene. (J:152368)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count