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A construct containing the CAGGS promoter driving expression of a loxP-flanked EGFP with a polyA STOP sequence, followed by the (canonical) coding sequence of Pax6 and an IRES-lacZ-polyA cassette was used to generate the mouse line. The allele ubiquitously expresses EGFP. When these mice are crossed to a cre recombinase-expressing line, the STOP-EGFP sequence is excised, allowing coexpression of Pax6 and lacZ. (J:135032)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
