Log In|Sign Up
EN
Exon 5 was replaced with one in which a point mutation results in an amino acid substitution of arginine for lysine at position 805 (K805R). A floxed neo cassette was used for selection purposes and removed by germ line, cre-mediated recombination. The predicted protein is expected to be a kinase dead version. (J:152332)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
