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The transgenic construct contains the KRT14 promoter/enhancer followed by the cre recombinase cDNA fused to the sequence of an altered hormone-binding domain of the mouse estrogen receptor (cre/Ert). The transgene also contains a rabbit beta-globin 5' UTR region and intronic sequence 5' to the cre cDNA, as well as the KRT14 3' UTR and polyadenylation site 3' to the cre sequence. The construct was injected into FVB/N zygotes. Three founders were identified. (J:150033)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
